Y-27632 dihydrochloride
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Y-27632 dihydrochloride |
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A3008-200 | ApexBio | 200 mg | EUR 1284 |
Description: Y-27632 dihydrochloride is a small-molecule inhibitor of Rho-associated protein kinase p160ROCK with the IC50 of 140 nM. Y-27632 suppresses the kinase activity of both ROCK-1 and ROCK-2 in vitro, and this compound inhibits the kinases by binding to the catalytic site of ROCK-1 and ROCK-2. |
Y-27632 dihydrochloride |
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A3008-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 177.6 |
Description: Y-27632 dihydrochloride is a small-molecule inhibitor of Rho-associated protein kinase p160ROCK with the IC50 of 140 nM. Y-27632 suppresses the kinase activity of both ROCK-1 and ROCK-2 in vitro, and this compound inhibits the kinases by binding to the catalytic site of ROCK-1 and ROCK-2. |
Y-27632 dihydrochloride |
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A3008-50 | ApexBio | 50 mg | EUR 505.2 |
Description: Y-27632 dihydrochloride is a small-molecule inhibitor of Rho-associated protein kinase p160ROCK with the IC50 of 140 nM. Y-27632 suppresses the kinase activity of both ROCK-1 and ROCK-2 in vitro, and this compound inhibits the kinases by binding to the catalytic site of ROCK-1 and ROCK-2. |
Y-27632 dihydrochloride |
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GK8578-1MG | Glentham Life Sciences | 1 mg | EUR 170.4 |
Y-27632 dihydrochloride |
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GK8578-25MG | Glentham Life Sciences | 25 mg | EUR 945.6 |
Y-27632 dihydrochloride |
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GK8578-5MG | Glentham Life Sciences | 5 mg | EUR 399.6 |
Y-27632 (dihydrochloride) |
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HY-10583 | MedChemExpress | 50mg | EUR 349.2 |
Y-39983 dihydrochloride |
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B1176-10 | ApexBio | 10 mg | EUR 494.4 |
Description: Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK [1]. |
Y-39983 dihydrochloride |
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B1176-100 | ApexBio | 100 mg | EUR 2881.2 |
Description: Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK [1]. |
Y-39983 dihydrochloride |
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B1176-5 | ApexBio | 5 mg | EUR 320.4 |
Description: Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK [1]. |
Y-39983 dihydrochloride |
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B1176-50 | ApexBio | 50 mg | EUR 1796.4 |
Description: Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK [1]. |
Y-33075 (dihydrochloride) |
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HY-10069 | MedChemExpress | 5mg | EUR 258 |
H89 Dihydrochloride |
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20-abx076747 | Abbexa |
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MPP dihydrochloride |
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B6910-10 | ApexBio | 10 mg | EUR 381.6 |
MPP dihydrochloride |
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B6910-50 | ApexBio | 50 mg | EUR 1413.6 |
SAG dihydrochloride |
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GL1175-1MG | Glentham Life Sciences | 1 mg | EUR 234 |
SAG dihydrochloride |
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GL1175-5MG | Glentham Life Sciences | 5 mg | EUR 688.8 |
TMB (dihydrochloride) |
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HY-15930A | MedChemExpress | 10mM/1mL | EUR 135.6 |
TMB dihydrochloride |
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TB0514 | Bio Basic | 1g | EUR 85.06 |
1400W dihydrochloride |
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2055-25 | Biovision | each | EUR 405.6 |
1400W dihydrochloride |
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2055-5 | Biovision | each | EUR 151.2 |
DMPQ Dihydrochloride |
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20-abx076714 | Abbexa |
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IT1t dihydrochloride |
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B5650-10 | ApexBio | 10 mg | EUR 385.2 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
IT1t dihydrochloride |
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B5650-100 | ApexBio | 100 mg | EUR 2100 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
IT1t dihydrochloride |
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B5650-25 | ApexBio | 25 mg | EUR 710.4 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
IT1t dihydrochloride |
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B5650-5 | ApexBio | 5 mg | EUR 243.6 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
IT1t dihydrochloride |
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B5650-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 261.6 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
IT1t dihydrochloride |
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B5650-50 | ApexBio | 50 mg | EUR 1232.4 |
Description: IT1t dihydrochloride is a potent antagonist of CXCR4 with IC50 value of 8.0 nM [1]. C-X-C chemokine receptor type 4 (CXCR4) is an ?-chemokine receptor for chemokine CXCL12. |
DMPQ dihydrochloride |
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B6642-10 | ApexBio | 10 mg | EUR 223.2 |
DMPQ dihydrochloride |
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B6642-5 | ApexBio | 5 mg | EUR 184.8 |
GNTI dihydrochloride |
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B6669-10 | ApexBio | 10 mg | EUR 459.6 |
GNTI dihydrochloride |
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B6669-50 | ApexBio | 50 mg | EUR 1746 |
1400W dihydrochloride |
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B6730-10 | ApexBio | 10 mg | EUR 170.4 |
Description: 1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase with Kd value of 7 nM [1]. Inducible nitric oxide synthase (iNOS) is an enzyme catalyzing the production of nitric oxide (NO) and is involved in immune response. |
1400W dihydrochloride |
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B6730-100 | ApexBio | 100 mg | EUR 873.6 |
Description: 1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase with Kd value of 7 nM [1]. Inducible nitric oxide synthase (iNOS) is an enzyme catalyzing the production of nitric oxide (NO) and is involved in immune response. |
1400W dihydrochloride |
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B6730-50 | ApexBio | 50 mg | EUR 525.6 |
Description: 1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase with Kd value of 7 nM [1]. Inducible nitric oxide synthase (iNOS) is an enzyme catalyzing the production of nitric oxide (NO) and is involved in immune response. |
1400W dihydrochloride |
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GK6799-100MG | Glentham Life Sciences | 100 mg | EUR 661.2 |
1400W dihydrochloride |
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GK6799-25MG | Glentham Life Sciences | 25 mg | EUR 274.8 |
1400W dihydrochloride |
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GK6799-5MG | Glentham Life Sciences | 5 mg | EUR 136.8 |
PAβN (dihydrochloride) |
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HY-101444A | MedChemExpress | 10mM/1mL | EUR 154.8 |
IT1t (dihydrochloride) |
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HY-101458A | MedChemExpress | 10mg | EUR 308.4 |
1400W (Dihydrochloride) |
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HY-18731 | MedChemExpress | 10mM/1mL | EUR 151.2 |
DAPI (dihydrochloride) |
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HY-D0814 | MedChemExpress | 50mg | EUR 439.2 |
CP 31398 dihydrochloride |
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A4476-10 | ApexBio | 10 mg | EUR 381.6 |
Description: CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm [2].Tumor protein p53 (p53) is a crucial protein in multicellular organisms and plays an important role in preventing cancer formation. |
CP 31398 dihydrochloride |
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A4476-50 | ApexBio | 50 mg | EUR 1413.6 |
Description: CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm [2].Tumor protein p53 (p53) is a crucial protein in multicellular organisms and plays an important role in preventing cancer formation. |
AZ 12080282 dihydrochloride |
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A8657-10 | ApexBio | 10 mg | EUR 498 |
Description: AZ 12080282 dihydrochloride is a selective inhibitor of Hh with IC50 value <0.012 ?M [1]. It is also reported that AZ 12080282 also has a selective inhibition to p38? with low nanomolar potency [1]. |
AZ 12080282 dihydrochloride |
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A8657-50 | ApexBio | 50 mg | EUR 1900.8 |
Description: AZ 12080282 dihydrochloride is a selective inhibitor of Hh with IC50 value <0.012 ?M [1]. It is also reported that AZ 12080282 also has a selective inhibition to p38? with low nanomolar potency [1]. |
AY 9944 dihydrochloride |
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A8658-10 | ApexBio | 10 mg | EUR 289.2 |
Description: AY 9944 dihydrochloride is a selective inhibitor of ?7-sterol reductase with IC50 value of 13 nM [1].?7-sterol reductase (Dhcr7) is an enzyme and plays an important role in catalyzing the production of cholesterol from 7-Dehydrocholesterol through using NADPH [2, 3]. |
AY 9944 dihydrochloride |
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A8658-25 | ApexBio | 25 mg | EUR 582 |
Description: AY 9944 dihydrochloride is a selective inhibitor of ?7-sterol reductase with IC50 value of 13 nM [1].?7-sterol reductase (Dhcr7) is an enzyme and plays an important role in catalyzing the production of cholesterol from 7-Dehydrocholesterol through using NADPH [2, 3]. |
AY 9944 dihydrochloride |
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A8658-5 | ApexBio | 5 mg | EUR 184.8 |
Description: AY 9944 dihydrochloride is a selective inhibitor of ?7-sterol reductase with IC50 value of 13 nM [1].?7-sterol reductase (Dhcr7) is an enzyme and plays an important role in catalyzing the production of cholesterol from 7-Dehydrocholesterol through using NADPH [2, 3]. |
GBR 12935 dihydrochloride |
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B4661-10 | ApexBio | 10 mg | EUR 129.6 |
GBR 12935 dihydrochloride |
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B4661-100 | ApexBio | 100 mg | EUR 296.4 |
GBR 12935 dihydrochloride |
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B4661-50 | ApexBio | 50 mg | EUR 192 |
ETP 45835 dihydrochloride |
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B4938-10 | ApexBio | 10 mg | EUR 428.4 |
ETP 45835 dihydrochloride |
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B4938-50 | ApexBio | 50 mg | EUR 1608 |
AZ 10606120 dihydrochloride |
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B5410-10 | ApexBio | 10 mg | EUR 408 |
Description: KD: 1.4 nM and 1.9 nM for human and rat P2X7 receptors, respectivleyThe P2X7 receptor has intriguing biophysical properties, activates a diverse range of cellular events and mediates a wide range of functional effects. |
AZ 10606120 dihydrochloride |
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B5410-50 | ApexBio | 50 mg | EUR 1531.2 |
Description: KD: 1.4 nM and 1.9 nM for human and rat P2X7 receptors, respectivleyThe P2X7 receptor has intriguing biophysical properties, activates a diverse range of cellular events and mediates a wide range of functional effects. |
CP 99994 dihydrochloride |
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B5422-10 | ApexBio | 10 mg | EUR 478.8 |
CP 99994 dihydrochloride |
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B5422-50 | ApexBio | 50 mg | EUR 1824 |
SB 243213 dihydrochloride |
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B5444-10 | ApexBio | 10 mg | EUR 486 |
SB 243213 dihydrochloride |
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B5444-50 | ApexBio | 50 mg | EUR 1802.4 |
JNJ 5207852 dihydrochloride |
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B5513-10 | ApexBio | 10 mg | EUR 289.2 |
JNJ 5207852 dihydrochloride |
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B5513-5 | ApexBio | 5 mg | EUR 180 |
JNJ 5207852 dihydrochloride |
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B5513-50 | ApexBio | 50 mg | EUR 1021.2 |
A 412997 dihydrochloride |
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B5639-25 | ApexBio | 25 mg | EUR 642 |
Description: A 412997 dihydrochloride is a selective agonist of dopamine D4 receptor with Ki values of 7.9 and 12.1 nM for human and rat D4 receptors, respectively [1]. Dopamine D4 receptor is a G protein-coupled receptor and is activated by dopamine. |
A 412997 dihydrochloride |
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B5639-5 | ApexBio | 5 mg | EUR 212.4 |
Description: A 412997 dihydrochloride is a selective agonist of dopamine D4 receptor with Ki values of 7.9 and 12.1 nM for human and rat D4 receptors, respectively [1]. Dopamine D4 receptor is a G protein-coupled receptor and is activated by dopamine. |