S63845 MCL 1 inhibitor
To Order Contact us: stephen@expresspharmapulse.com
Protease Inhibitor Cocktail |
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| R-1101 | EpiGentek |
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Mcl-1 Antibody |
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| 24298-100ul | SAB | 100ul | EUR 468 |
Mcl-1 Antibody |
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| 24299-100ul | SAB | 100ul | EUR 468 |
Mcl-1 Antibody |
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| 24300-100ul | SAB | 100ul | EUR 468 |
Mcl-1 Antibody |
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| 3477-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Antibody |
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| 3477-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Peptide |
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| 3477P | ProSci | 0.05 mg | EUR 197.7 |
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Description: (CT) Mcl-1 peptide |
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Mcl-1 Antibody |
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| 3479-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Antibody |
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| 3479-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Peptide |
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| 3479P | ProSci | 0.05 mg | EUR 197.7 |
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Description: (IN) Mcl-1 peptide |
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Mcl-1 Antibody |
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| 3481-002mg | ProSci | 0.02 mg | EUR 206.18 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Antibody |
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| 3481-01mg | ProSci | 0.1 mg | EUR 523.7 |
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Description: Mcl-1 Antibody: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death. |
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Mcl-1 Peptide |
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| 3481P | ProSci | 0.05 mg | EUR 197.7 |
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Description: (NT) Mcl-1 peptide |
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MCL-1 Antibody |
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| BF0080 | Affbiotech | 200ul | EUR 540 |
MCL-1 Antibody |
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| R30576 | NSJ Bioreagents | 100 ug | EUR 419 |
Mcl-1 Antibody |
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| 3035-100 | Biovision | each | EUR 379.2 |
Mcl-1 Antibody |
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| 3035-30T | Biovision | each | EUR 175.2 |
Mcl-1 Polyclonal Antibody |
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| ABP52891-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 |
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Mcl-1 Polyclonal Antibody |
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| ABP52891-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 |
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Mcl-1 Polyclonal Antibody |
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| ABP52891-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 |
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Mcl-1 Blocking Peptide |
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| AF4757-BP | Affbiotech | 1mg | EUR 234 |
Mcl-1 Polyclonal Antibody |
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| ES2760-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| ES2760-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| ES3890-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| ES3890-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| ES6206-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| ES6206-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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Mcl-1 Polyclonal Antibody |
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| 41124-100ul | SAB | 100ul | EUR 302.4 |
Mcl-1 Polyclonal Antibody |
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| 41124-50ul | SAB | 50ul | EUR 224.4 |
Mcl-1 Polyclonal Antibody |
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| ABP55207-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Monkey. This Mcl-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the non-phosphorylation site of S159 |
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Mcl-1 Polyclonal Antibody |
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| ABP55207-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Monkey. This Mcl-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the non-phosphorylation site of S159 |
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Mcl-1 Polyclonal Antibody |
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| ABP55207-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Monkey. This Mcl-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the non-phosphorylation site of S159 |
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Mcl-1 Polyclonal Antibody |
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| ABP51761-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 at AA range: 60-140 |
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Mcl-1 Polyclonal Antibody |
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| ABP51761-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 at AA range: 60-140 |
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Mcl-1 Polyclonal Antibody |
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| ABP51761-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Mcl-1 from Human, Mouse, Rat. This Mcl-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Mcl-1 at AA range: 60-140 |
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Polyclonal Mcl-1 Antibody |
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| APR08377G | Leading Biology | 0.1mg | EUR 580.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mcl-1 . This antibody is tested and proven to work in the following applications: |
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Polyclonal Mcl-1 Antibody |
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| APR08378G | Leading Biology | 0.1 mg | EUR 790.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mcl-1 . This antibody is tested and proven to work in the following applications: |
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Polyclonal Mcl-1 Antibody |
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| APR08379G | Leading Biology | 0.1 mg | EUR 790.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mcl-1 . This antibody is tested and proven to work in the following applications: |
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Polyclonal Mcl-1 Antibody |
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| APR08380G | Leading Biology | 0.1 mg | EUR 790.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mcl-1 . This antibody is tested and proven to work in the following applications: |
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MCL-1 Blocking Peptide |
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| BF0080-BP | Affbiotech | 1mg | EUR 234 |
anti-MCL-1 (8C6) |
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| LF-MA30025 | Abfrontier | 100 ul | EUR 534 |
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Description: Mouse Monoclonal to MCL-1 |
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Anti-Mcl-1 antibody |
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| STJ94044 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Mcl-1 is a protein encoded by the MCL1 gene which is approximately 37,3 kDa. Mcl-1 is localised to the cell membrane, cytoplasm, mitochondrion and nucleus. It is involved in apoptosis modulation and signalling, the Jak-STAT signalling pathway, cytokine signalling in the immune system and the PI3K-Akt signalling pathway. It regulated of apoptosis and cell survival, and plays a role in the maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes apoptosis. Mcl-1 is expressed in the nervous system, blood, lung, bone marrow and liver. Mutations in the MCL1 gene may result in myeloid leukaemia and follicular lymphoma. STJ94044 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Mcl-1 protein. |
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Anti-Mcl-1 antibody |
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| STJ94045 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Rabbit polyclonal to Mcl-1. |
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Anti-Mcl-1 antibody |
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| STJ96525 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Mcl-1 is a protein encoded by the MCL1 gene which is approximately 37,3 kDa. Mcl-1 is localised to the cytoplasm, mitochondrion and nucleus. It is involved in apoptosis modulation and signalling, the Jak-STAT signalling pathway, cytokine signalling in immune system and the PI3K-Akt signalling pathway. It is an anti-apoptotic protein, which is a member of the Bcl-2 family. Isoform 1 enhances cell survival by inhibiting apoptosis while Isoform 2 and isoform 3 promote apoptosis and are death-inducing. Mcl-1 is expressed in the cells of the nervous system, blood, lung, bone marrow and liver. Mutations in the MCL1 gene may result in myeloid leukaemia. STJ96525 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Mcl-1 protein. |
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Anti-Mcl-1 antibody |
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| STJ98232 | St John's Laboratory | 100 µl | EUR 280.8 |
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Description: Mouse monoclonal to Mcl-1. |
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Mcl-1 Blocking Peptide |
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| 3035BP-50 | Biovision | each | EUR 183.6 |
MCL-1 Peptide Ligand |
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| 79507 | BPS Bioscience | 400 rxns. | EUR 195 |
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Description: MCL-1 Peptide Ligand is useful as a substrate for screening services and optimized for use with the following TR-FRET assay kits: • MCL-1 TR-FRET Assay kit (BPS Bioscience #79506) • MCL-1 TR-FRET Assay kit (Mouse) (BPS Bioscience #79928) |
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HPGDS inhibitor 1 |
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| B1046-1 | ApexBio | 1 mg | EUR 217.2 |
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Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
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Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL-1) Antibody |
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| abx011122-100ul | Abbexa | 100 ul | EUR 493.2 |
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (Mcl-1) Antibody |
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| abx412149-01mg | Abbexa | 0.1 mg | EUR 844.8 |
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (Mcl-1) Antibody |
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| abx412627-01mg | Abbexa | 0.1 mg | EUR 610.8 |
Mcl-1 Polyclonal Conjugated Antibody |
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| C41124 | SAB | 100ul | EUR 476.4 |
Phospho- Mcl- 1 (Ser64) Antibody |
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| ABF3647 | Lifescience Market | 100 ug | EUR 525.6 |
MCL-1 His-Tag (Mouse) |
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| 100637 | BPS Bioscience | 100 µg | EUR 350 |
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Description: Mouse MCL-1, also known as Induced myeloid leukemia cell differentiation protein, GenBank Accession No. NM_008562, a.a. 2-308, with N-terminal His-tag, expressed in an E. coli expression system. MW=34 kDa. |
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187-1, N-WASP inhibitor |
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| B5251-1 | ApexBio | 1 mg | EUR 478.8 |
YAP-TEAD Inhibitor 1 (Peptide 17) |
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| A1149-1 | ApexBio | 1 mg | EUR 282 |
Phospho-Mcl-1 (Ser64) Blocking Peptide |
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| AF4457-BP | Affbiotech | 1mg | EUR 234 |
Mcl-1 (phospho Ser159) Polyclonal Antibody |
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| ES6205-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 (phospho Ser159) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
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Mcl-1 (phospho Ser159) Polyclonal Antibody |
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| ES6205-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Mcl-1 (phospho Ser159) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
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Mcl-1 (Phospho-Ser159) Polyclonal Antibody |
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| 12387-100ul | SAB | 100ul | EUR 302.4 |
Mcl-1 (Phospho-Ser159) Polyclonal Antibody |
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| 12387-50ul | SAB | 50ul | EUR 224.4 |
Mcl-1 (phospho Ser159) Polyclonal Antibody |
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| ABP55206-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159 |
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Mcl-1 (phospho Ser159) Polyclonal Antibody |
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| ABP55206-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159 |
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Mcl-1 (phospho Ser159) Polyclonal Antibody |
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| ABP55206-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Mcl-1 phospho Ser159) from Human, Mouse. This Mcl-1 phospho Ser159) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159 |
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Monoclonal Mcl-1 Antibody, Clone: Y37 |
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| APR08382G | Leading Biology | 0.1ml | EUR 633.6 |
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Description: A Monoclonal antibody against Human Mcl-1. The antibodies are raised in Rabbit and are from clone Y37. This antibody is applicable in IHC, WB |
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Anti-Phospho-Mcl-1 (S159) antibody |
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| STJ91350 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Rabbit polyclonal to Phospho-Mcl-1 (S159). |
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MCL-1 TR-FRET Assay Kit |
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| 79506 | BPS Bioscience | 384 rxns. | EUR 870 |
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Description: The MCL-1 TR-FRET Assay Kit is designed to measure the inhibition of MCL-1 binding to its ligand in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing terbium-labeled donor, dye-labeled acceptor, MCL-1, peptide ligand, and an inhibitor is incubated for 3 hours. Then, the fluorescence intensity is measured using a fluorescence reader. |
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Monoclonal PLA2G5 Antibody (clone MCL-3G1), Clone: MCL-3G1 |
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| AMR09323G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human PLA2G5 (clone MCL-3G1). The antibodies are raised in Mouse and are from clone MCL-3G1. This antibody is applicable in WB and IHC-P, IP |
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EGFR Inhibitor |
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| C3327-1 | ApexBio | 1 mg | EUR 184.8 |
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Description: EGFR inhibitor is a cell permeable, pyrimidine compound that selectively inhibits the EGFR kinase with IC50 value of 21 nM [1]. EGFR is a transmembrane protein, and is a receptor for members of epidermal growth factor family. |
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NFAT Inhibitor |
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| A4539-1 | ApexBio | 1 mg | EUR 165.6 |
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Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. |
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Lck Inhibitor |
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| A3539-1 | ApexBio | 1 mg | EUR 184.8 |
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Description: Lck Inhibitor is a small-molecule inhibitor of with IC50 value of 7 nM [1].The lymphocyte specific kinase which expressed in NK cells and T-cells is a member of the Src kinase family. |
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Stat5 Inhibitor |
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| 9484-1 | Biovision | each | EUR 144 |
Chk2 Inhibitor |
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| 1702-1 | Biovision | each | EUR 216 |