Endo Trap HD
To Order Contact us: stephen@expresspharmapulse.com
ENDO AGAR |
|||
E05-110-10kg | Alphabiosciences | 10 kg | EUR 2857.2 |
ENDO AGAR |
|||
E05-110-2Kg | Alphabiosciences | 2 Kg | EUR 668.4 |
ENDO AGAR |
|||
E05-110-500g | Alphabiosciences | 500 g | EUR 225.6 |
TRAP-6 |
|||
A8675-5 | ApexBio | 5 mg | EUR 207.6 |
Description: Peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. Stimulates platelet aggregation (EC50 = 0.8 ?M), promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation |
TRAP Antibody |
|||
6911-002mg | ProSci | 0.02 mg | EUR 206.18 |
Description: TRAP Antibody: TRAP, also known as uteroferrin, is an iron containing, glycosylated, acid phosphatase. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. Along with the related protein ACP2, TRAP mediates the removal of mannose 6-phosphate residues from proteins targeted to lysosomes. TRAP is present in brain at low levels, but is expressed at a much higher level in liver. |
TRAP Antibody |
|||
6911-01mg | ProSci | 0.1 mg | EUR 523.7 |
Description: TRAP Antibody: TRAP, also known as uteroferrin, is an iron containing, glycosylated, acid phosphatase. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. Along with the related protein ACP2, TRAP mediates the removal of mannose 6-phosphate residues from proteins targeted to lysosomes. TRAP is present in brain at low levels, but is expressed at a much higher level in liver. |
TRAP Peptide |
|||
6911P | ProSci | 0.05 mg | EUR 197.7 |
Description: (CT) TRAP peptide |
TRAP-14 |
|||
5-02017 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP antibody |
|||
70R-12535 | Fitzgerald | 100 ul | EUR 548.4 |
Description: Affinity purified Rabbit polyclonal TRAP antibody |
TRAP antibody |
|||
22406-100ul | SAB | 100ul | EUR 468 |
TRAP Antibody |
|||
25505-100ul | SAB | 100ul | EUR 468 |
TRAP -6 |
|||
ABP-TRA-1 | Abpcorp | 5,0mg vial | EUR 204 |
Trap 101 |
|||
B7084-10 | ApexBio | 10 mg | EUR 447.6 |
Trap 101 |
|||
B7084-50 | ApexBio | 50 mg | EUR 1635.6 |
TRAP-6 |
|||
HY-P0078 | MedChemExpress | 10mM/1mL | EUR 386.4 |
TRAP-6 |
|||
H-7764.0500 | Bachem | 0.5mg | EUR 57.6 |
Description: Sum Formula: C34H56N10O9; CAS# [141136-83-6] net |
TRAP-6 |
|||
H-7764.1000 | Bachem | 1.0mg | EUR 72 |
Description: Sum Formula: C34H56N10O9; CAS# [141136-83-6] net |
TRAP-14 |
|||
H-8105.0001 | Bachem | 1.0mg | EUR 181.2 |
Description: Sum Formula: C81H118N20O23; CAS# [137339-65-2] net |
TRAP-14 |
|||
H-8105.0005 | Bachem | 5.0mg | EUR 618 |
Description: Sum Formula: C81H118N20O23; CAS# [137339-65-2] net |
TRAP-6 |
|||
H-8365.0005 | Bachem | 5.0mg | EUR 327.6 |
Description: Sum Formula: C34H56N10O9; CAS# [141136-83-6] net |
TRAP-6 |
|||
H-8365.0025 | Bachem | 25.0mg | EUR 1197.6 |
Description: Sum Formula: C34H56N10O9; CAS# [141136-83-6] net |
TRAP-7 |
|||
H-2234.0005 | Bachem | 5.0mg | EUR 646.8 |
Description: Sum Formula: C39H63N11O10; CAS# [145229-76-1] net |
TRAP-7 |
|||
H-2234.0025 | Bachem | 25.0mg | EUR 2473.2 |
Description: Sum Formula: C39H63N11O10; CAS# [145229-76-1] net |
TRAP-5 |
|||
H-1408.0005 | Bachem | 5.0mg | EUR 691.2 |
Description: Sum Formula: C30H50N8O7; CAS# [141685-53-2] net |
TRAP-5 |
|||
H-1408.0025 | Bachem | 25.0mg | EUR 2648.4 |
Description: Sum Formula: C30H50N8O7; CAS# [141685-53-2] net |
Rat(TRAP) |
|||
QY-E11743 | Qayee Biotechnology | 96T | EUR 448.8 |
pTALETF_v2 HD Plasmid |
|||
PVT6207 | Lifescience Market | 2 ug | EUR 319.2 |
pTALEN_v2 HD Plasmid |
|||
PVT6211 | Lifescience Market | 2 ug | EUR 614.4 |
Endo G Antibody |
|||
DF8541 | Affbiotech | 200ul | EUR 420 |
Endo G Antibody |
|||
45339-100ul | SAB | 100ul | EUR 302.4 |
Endo G Antibody |
|||
45339-50ul | SAB | 50ul | EUR 224.4 |
Endo G Antibody |
|||
49763-100ul | SAB | 100ul | EUR 399.6 |
Endo G Antibody |
|||
49763-50ul | SAB | 50ul | EUR 286.8 |
Endo G Antibody |
|||
ABD8541 | Lifescience Market | 100 ug | EUR 525.6 |
IWR-1-endo |
|||
B2306-10 | ApexBio | 10 mg | EUR 157.2 |
Description: IWR-1-endo is a small molecule inhibitor of Wnt Response with IC50 value of 180nM [1].IWR-1-endo is a small molecule antagonists of the Wnt/?-catenin pathway screened out from a diverse synthetic chemical library. |
IWR-1-endo |
|||
B2306-25 | ApexBio | 25 mg | EUR 268.8 |
Description: IWR-1-endo is a small molecule inhibitor of Wnt Response with IC50 value of 180nM [1].IWR-1-endo is a small molecule antagonists of the Wnt/?-catenin pathway screened out from a diverse synthetic chemical library. |
IWR-1-endo |
|||
B2306-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: IWR-1-endo is a small molecule inhibitor of Wnt Response with IC50 value of 180nM [1].IWR-1-endo is a small molecule antagonists of the Wnt/?-catenin pathway screened out from a diverse synthetic chemical library. |
ENDO-Growth Media |
|||
MED001 | Neuromics | 500 ml | EUR 434.4 |
ENDO Basal Media |
|||
MED002 | Neuromics | 500 ml | EUR 248.4 |
ENDO-Growth Supplements |
|||
EGS001 | Neuromics | 25 ml | EUR 292.8 |
anti-Endo G |
|||
YF-PA11561 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to Endo G |
anti-Endo G |
|||
YF-PA11562 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to Endo G |
TRAP Conjugated Antibody |
|||
C44711 | SAB | 100ul | EUR 476.4 |
TRAP Conjugated Antibody |
|||
C36331 | SAB | 100ul | EUR 476.4 |
TRAP Conjugated Antibody |
|||
C38129 | SAB | 100ul | EUR 476.4 |
[Cit5]-TRAP-5 |
|||
5-00062 | CHI Scientific | 4 x 5mg | Ask for price |
[Tyr1]-TRAP-7 |
|||
5-00339 | CHI Scientific | 4 x 5mg | Ask for price |
Scrambled TRAP Fragment |
|||
5-01910 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP-14 amide |
|||
5-02018 | CHI Scientific | 4 x 1mg | Ask for price |
TRAP-5 amide |
|||
5-02019 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP-14 Peptide |
|||
20-abx266463 | Abbexa |
|
|
Polyclonal TRAP Antibody |
|||
APR10538G | Leading Biology | 0.1 mg | EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TRAP . This antibody is tested and proven to work in the following applications: |
TRAP-14 amide |
|||
H-6032.0001 | Bachem | 1.0mg | EUR 254.4 |
Description: Sum Formula: C81H119N21O22; CAS# [141923-36-6] net |
TRAP-14 amide |
|||
H-6032.0005 | Bachem | 5.0mg | EUR 907.2 |
Description: Sum Formula: C81H119N21O22; CAS# [141923-36-6] net |
TRAP-6 amide |
|||
H-2936.0005 | Bachem | 5.0mg | EUR 138 |
Description: Sum Formula: C34H57N11O8; CAS# [141923-40-2] net |
TRAP-6 amide |
|||
H-2936.0025 | Bachem | 25.0mg | EUR 441.6 |
Description: Sum Formula: C34H57N11O8; CAS# [141923-40-2] net |
TRAP-5 amide |
|||
H-2938.0025 | Bachem | 25.0mg | EUR 646.8 |
Description: Sum Formula: C30H51N9O6; CAS# [141923-41-3] net |
TRAP-5 amide |
|||
H-2938.0100 | Bachem | 100.0mg | EUR 1864.8 |
Description: Sum Formula: C30H51N9O6; CAS# [141923-41-3] net |
(Tyr1)-TRAP-7 |
|||
H-1674.0001 | Bachem | 1.0mg | EUR 151.2 |
Description: Sum Formula: C45H67N11O10; CAS# [149440-16-4] net |
(Tyr1)-TRAP-7 |
|||
H-1674.0005 | Bachem | 5.0mg | EUR 501.6 |
Description: Sum Formula: C45H67N11O10; CAS# [149440-16-4] net |
CD40 Ligand/TRAP |
|||
PR29002 | Neuromics | 50 ug | EUR 589.2 |
Anti-TRAP antibody |
|||
STJ190098 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Unconjugated Mouse monoclonal to TRAP (2H2) |
anti-TRAP alpha |
|||
YF-PA14790 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to TRAP alpha |
anti-TRAP alpha |
|||
YF-PA14791 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to TRAP alpha |
Gst Spin Trap |
|||
28952359 | Scientific Laboratory Supplies | PK50 | EUR 448.02 |
TRAP Antibody (CD40L) |
|||
F49677-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
TRAP Antibody (CD40L) |
|||
F49677-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
Mouse HD ELISA Kit |
|||
EMH0241 | Abclonal | 96Tests | EUR 625.2 |
Human HD ELISA Kit |
|||
EHH0241 | Abclonal | 96Tests | EUR 625.2 |
Rat HD ELISA Kit |
|||
ERH0241 | Abclonal | 96Tests | EUR 625.2 |
Rabbit HD ELISA Kit |
|||
ERTH0241 | Abclonal | 96Tests | EUR 625.2 |
Porcine HD ELISA Kit |
|||
EPH0241 | Abclonal | 96Tests | EUR 625.2 |
Goat HD ELISA Kit |
|||
EGTH0241 | Abclonal | 96Tests | EUR 625.2 |
Bovine HD ELISA Kit |
|||
EBH0241 | Abclonal | 96Tests | EUR 625.2 |
Canine HD ELISA Kit |
|||
ECH0241 | Abclonal | 96Tests | EUR 625.2 |
Anserini HD ELISA Kit |
|||
EAH0241 | Abclonal | 96Tests | EUR 625.2 |
Foam bung 38x50mm hd |
|||
FOB010 | Scientific Laboratory Supplies | PK100 | EUR 33.63 |
Tubes 50ml Conical HD |
|||
X13758 | Scientific Laboratory Supplies | PK12 | EUR 197.22 |
Endo G Rabbit mAb |
|||
A8801 | Abclonal | 20 μL | EUR 18 |
Endo G Blocking Peptide |
|||
DF8541-BP | Affbiotech | 1mg | EUR 234 |
Endo G Conjugated Antibody |
|||
C49763 | SAB | 100ul | EUR 476.4 |
Endo G Conjugated Antibody |
|||
C45339 | SAB | 100ul | EUR 476.4 |
M-ENDO AGAR, LES |
|||
M13-124-10kg | Alphabiosciences | 10 kg | EUR 3082.8 |
M-ENDO AGAR, LES |
|||
M13-124-2Kg | Alphabiosciences | 2 Kg | EUR 717.6 |
M-ENDO AGAR, LES |
|||
M13-124-500g | Alphabiosciences | 500 g | EUR 238.8 |
ENDO-Growth Media Kit |
|||
EGK001 | Neuromics | 500 ml | EUR 434.4 |
Endo-38a-Pro-Exenatide |
|||
H-7492.0100 | Bachem | 0.1mg | EUR 163.2 |
Description: Sum Formula: C189H289N51O61S; CAS# [1678416-95-9] net |
Endo-38a-Pro-Exenatide |
|||
H-7492.0500 | Bachem | 0.5mg | EUR 542.4 |
Description: Sum Formula: C189H289N51O61S; CAS# [1678416-95-9] net |
(1R)-Endo-(+)-Fenchyl Alc |
|||
S-7604 | Scientific Laboratory Supplies | EACH | EUR 69.54 |
Falcon Hd Translucent 3um Hd Pet Membrane For 12 Well Plate |
|||
353292 | Scientific Laboratory Supplies | PK48 | EUR 387.6 |
Falcon Hd Translucent 3um Hd Pet Membrane For 24 Well Plate |
|||
353492 | Scientific Laboratory Supplies | PK48 | EUR 387.6 |
Falcon Hd Translucent 0.4um Hd Pet Membrane For 24 Well Plate |
|||
353493 | Scientific Laboratory Supplies | PK48 | EUR 449.16 |
Falcon Hd Translucent 0.45um Hd Pet Membrane For 12 Well Plate |
|||
353494 | Scientific Laboratory Supplies | PK48 | EUR 387.6 |
Falcon Hd Translucent 0.45um Hd Pet Membrane For 24 Well Plate |
|||
353495 | Scientific Laboratory Supplies | PK48 | EUR 384.18 |
Sheep TRAP ELISA Kit |
|||
EST0544 | Abclonal | 96Tests | EUR 625.2 |
Human TRAP ELISA Kit |
|||
EHT0544 | Abclonal | 96Tests | EUR 625.2 |
Porcine TRAP ELISA Kit |
|||
EPT0544 | Abclonal | 96Tests | EUR 625.2 |
Monkey TRAP ELISA Kit |
|||
EMKT0544 | Abclonal | 96Tests | EUR 625.2 |
Mouse TRAP ELISA Kit |
|||
EMT0544 | Abclonal | 96Tests | EUR 625.2 |
Rat TRAP ELISA Kit |
|||
ERT0544 | Abclonal | 96Tests | EUR 625.2 |
[Phe1, Ser2]-TRAP-6 |
|||
5-00263 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP-6 (2-6) |
|||
5-02020 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP-5 amide Peptide |
|||
20-abx265852 | Abbexa |
|
|
Scrambled TRAP Fragment Peptide |
|||
20-abx265858 | Abbexa |
|
|
[Tyr1]-TRAP-7 Peptide |
|||
20-abx265889 | Abbexa |
|
|
[Cit5]-TRAP-5 Peptide |
|||
20-abx265945 | Abbexa |
|
|
Anti-TRAP Monoclonal Antibody |
|||
M03277-1 | BosterBio | 100ug | EUR 476.4 |
Description: Rabbit Monoclonal TRAP Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
Goat TRAP ELISA Kit |
|||
EGTT0544 | Abclonal | 96Tests | EUR 625.2 |
Bovine TRAP ELISA Kit |
|||
EBT0544 | Abclonal | 96Tests | EUR 625.2 |
Mouse TRAP ELISA Kit |
|||
ELI-03023m | Lifescience Market | 96 Tests | EUR 1038 |
(Phe1,Ser2)-TRAP-6 |
|||
H-5996.0005 | Bachem | 5.0mg | EUR 356.4 |
Description: Sum Formula: C34H56N10O9; CAS# [374898-11-0] net |
(Phe1,Ser2)-TRAP-6 |
|||
H-5996.0025 | Bachem | 25.0mg | EUR 1311.6 |
Description: Sum Formula: C34H56N10O9; CAS# [374898-11-0] net |
TRAP-6 (2-6) |
|||
H-8325.0005 | Bachem | 5.0mg | EUR 327.6 |
Description: Sum Formula: C31H51N9O7; CAS# [141136-84-7] net |
TRAP-6 (2-6) |
|||
H-8325.0025 | Bachem | 25.0mg | EUR 1197.6 |
Description: Sum Formula: C31H51N9O7; CAS# [141136-84-7] net |
(DL-Isoser1)-TRAP-6 |
|||
H-1944.0001 | Bachem | 1.0mg | EUR 327.6 |
Description: Sum Formula: C34H56N10O9; CAS# [150242-29-8] net |
(DL-Isoser1)-TRAP-6 |
|||
H-1944.0005 | Bachem | 5.0mg | EUR 1197.6 |
Description: Sum Formula: C34H56N10O9; CAS# [150242-29-8] net |
Chicken TRAP ELISA Kit |
|||
ECKT0544 | Abclonal | 96Tests | EUR 625.2 |
Canine TRAP ELISA Kit |
|||
ECT0544 | Abclonal | 96Tests | EUR 625.2 |
CD40 Ligand/TRAP (Soluble) |
|||
PR27033 | Neuromics | 50 ug | EUR 608.4 |
Anti-TRAP alpha (1C11) |
|||
YF-MA15622 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to TRAP alpha |
Anti-TRAP alpha (1A12) |
|||
YF-MA10883 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to TRAP alpha |
VENT FILTER / C02 TRAP |
|||
ZFRE012FC | Scientific Laboratory Supplies | EACH | EUR 440.04 |
TRAP-1 Antibody / HSP75 |
|||
R32204 | NSJ Bioreagents | 100 ug | EUR 419 |
CD40L Antibody / TRAP / CD154 |
|||
RQ4070 | NSJ Bioreagents | 100 ug | EUR 419 |
Cd40l Antibody / Trap / Cd154 |
|||
RQ4071 | NSJ Bioreagents | 100 ug | EUR 419 |
CD40L Antibody / TRAP / CD154 |
|||
RQ4900 | NSJ Bioreagents | 100ug | EUR 419 |
TRAcP Antibody / TRAP / ACP5 |
|||
RQ5412 | NSJ Bioreagents | 100 ul | EUR 419 |
CD40L Antibody / TRAP / CD154 |
|||
V8248-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V8248-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V8248SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD154 Antibody / CD40L / TRAP |
|||
RQ6411 | NSJ Bioreagents | 100 ug | EUR 419 |
Description: CD154 (CD40 ligand) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD154 with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since it is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble for of the protein may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells. CD154 plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions. |
Cd40l Antibody / Trap / Cd154 |
|||
RQ6604 | NSJ Bioreagents | 100ug | EUR 419 |
Description: CD40 ligand (CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumor necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells. CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions. |
TRAP-1 Antibody / HSP75 |
|||
RQ6811 | NSJ Bioreagents | 100ug | EUR 419 |
Description: Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3. |
ACP5/TRAP, human recombinant |
|||
P1055-10 | Biovision | each | EUR 196.8 |
ACP5/TRAP, human recombinant |
|||
P1055-50 | Biovision | each | EUR 705.6 |
TRAcP Antibody / TRAP / ACP5 |
|||
F47709-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
TRAcP Antibody / TRAP / ACP5 |
|||
F47709-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
TRAP-1 Antibody (HSP75) |
|||
F43545-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
TRAP-1 Antibody (HSP75) |
|||
F43545-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
TRAcP Antibody / TRAP / ACP5 |
|||
V7136-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: Tartrate-Resistant Acid Phosphatase is involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. [UniProt] |
TRAcP Antibody / TRAP / ACP5 |
|||
V7136-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: Tartrate-Resistant Acid Phosphatase is involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. [UniProt] |
TRAcP Antibody / TRAP / ACP5 |
|||
V7136SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: Tartrate-Resistant Acid Phosphatase is involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. [UniProt] |
CD40L Antibody / TRAP / CD154 |
|||
V7385-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V7385-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V7385IHC-7ML | NSJ Bioreagents | 7 ml | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V7385SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2794-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2794-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2794SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2795-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2795-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V2795SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3534-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3534-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3534IHC-7ML | NSJ Bioreagents | 7 ml | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3534SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3535-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3535-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3535IHC-7ML | NSJ Bioreagents | 7 ml | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
TRAcP Antibody / TRAP / ACP5 |
|||
V3535SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher’s Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts. |
CD40L Antibody / TRAP / CD154 |
|||
V8828-100UG | NSJ Bioreagents | 100ug | EUR 499 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |
CD40L Antibody / TRAP / CD154 |
|||
V8828-20UG | NSJ Bioreagents | 20ug | EUR 219 |
Description: CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells. |