MK-5 with vented cover (polycarbonate
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 MK-0974 |
|
A3612-5 |
ApexBio |
5 mg |
EUR 474 |
|
Description: MK-0974 (Telcagepant) is a highly potent, selective, and orally bioavailable antagonist of CGRP receptor with IC50 value of 0.77 nM [1]. |
 MK-2894 |
|
A3613-5 |
ApexBio |
5 mg |
EUR 428.4 |
|
Description: MK-2894 is a highly potent and selective inhibitor of EP4 receptor with IC50 value of 2.5 nM [1]. |
 MK-3207 |
|
A3615-5 |
ApexBio |
5 mg |
EUR 408 |
|
Description: MK-3207 is a new, highly selective CGRP receptor antagonist that is approximately 40- to 65-fold more potent than telcagepant for the human CGRP receptor. The IC50 is 0.12 nM and The Ki value is 0.024 nM. It is highly selective versus human AM1, AM2, CTR, and AMY3. |
 MK-4827 |
|
A3617-5 |
ApexBio |
5 mg |
EUR 250.8 |
|
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1]. |
 MK-5172 |
|
A3618-5 |
ApexBio |
5 mg |
EUR 184.8 |
|
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2]. |
 MK-6892 |
|
A3623-5 |
ApexBio |
5 mg |
EUR 602.4 |
|
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent |
 MK-8033 |
|
A3624-5 |
ApexBio |
5 mg |
EUR 559.2 |
|
Description: MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. |
 MK 886 |
|
B6684-5 |
ApexBio |
5 mg |
EUR 164.4 |
 MK-4101 |
|
B7803-5 |
ApexBio |
5 mg |
EUR 313.2 |
|
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma. |
 MK 571 |
|
B7023-5 |
ApexBio |
5 mg |
EUR 153.6 |
|
Description: MK 571 (L-660,711) is a novel potent and selective antagonist of leukotriene D4 receptor with Ki values of 0.22 nM and 2.1 nM in guinea pig and human lung membranes, respectively [1]. |
MK-5 with vented cover (polycarbonate
