MK-5 with vented cover (polycarbonate 

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MK-7655

B2289-5
EUR 196

MK-0557

B2317-5
EUR 196

MK-3903

B2431-5
EUR 414

MK-886

B2517-5
EUR 175

MK-0941

B1207-5
EUR 185

MK-8931

B1315-5
EUR 512

MK-5108

B1344-5
EUR 262

MK-3102

9599-5
EUR 457

MK-4827

9462-5
EUR 305

MK 886

B6684-5 5 mg
EUR 137

MK 571

B7023-5 5 mg
EUR 128
Description: MK 571 (L-660,711) is a novel potent and selective antagonist of leukotriene D4 receptor with Ki values of 0.22 nM and 2.1 nM in guinea pig and human lung membranes, respectively [1].

MK-4101

B7803-5 5 mg
EUR 261
Description: IC50: 1.5 ?mol/L for in mouse Light II cells by Gli_luc assayMK-4101 is a Hedgehog (Hh) signaling pathway inhibitor.Abnormal activation of the Hedgehog (Hh) signaling pathway is reported in the pathogenesis of various cancers, such as medulloblastoma and basal cell carcinoma.

MK-0752

A4006-5 5 mg
EUR 247
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-2048

A4072-5 5 mg
EUR 270
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-8245

A4345-5 5 mg
EUR 268
Description: MK-8245 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase (SCD) with IC50 value of 1nM [1].SCD1 represents a therapeutic target for the treatment of type II diabetes, dyslipidemia, obesity, and metabolic diseases.

MK-1775

A5755-5 5 mg
EUR 148
Description: MK-1775 is a potent and selective Wee1 inhibitor with an IC50 of 5.2 nM in a cell-free assay. MK-1775 abolishes cyclin-dependent kinase 1 (CDC2) activity by phosphorylation of the Tyr15 residue [1].

MK-2461

A8476-5 5 mg
EUR 268
Description: MK-2461 is a potent inhibitor of Met, Flt1, Flt 3, Ron, PDGFR?, and Mer with IC50 of 2.5 nM, 10 nM, 22 nM, 7 nM, and 24 nM, respectively.

MK 6096

A8953-5 5 mg
EUR 321
Description: MK 6096

MK 0893

A3608-5 5 mg
EUR 415
Description: MK 0893 is an inhibitor of both glucagon receptor and IGF-1R with IC50 values of 6.6nM and 6nM, respectively [1, 2].

MK-0591

A3609-5 5 mg
EUR 284
Description: MK-0591, an analog of MK-886 is a potent and orally active leukotriene biosynthesis inhibitor with an IC50 value of 600 ng/ml.

MK-0812

A3611-5 5 mg
EUR 379
Description: MK-0812 is an antagonist of chemokine receptor CCR-2 [1].C-C chemokine receptor type 2 (CCR-2) is a chemokine receptor expressing on monocytes and macrophages and plays a critical and apparently non-redundant role in orchestrating the trafficking of monocytes to tissues [1].

MK-0974

A3612-5 5 mg
EUR 395
Description: MK-0974 (Telcagepant) is a highly potent, selective, and orally bioavailable antagonist of CGRP receptor with IC50 value of 0.77 nM [1].

MK-5 with vented cover (polycarbonate