MK-5 with vented cover (polycarbonate 

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MK-2894

A3613-5 5 mg
EUR 357
Description: MK-2894 is a highly potent and selective inhibitor of EP4 receptor with IC50 value of 2.5 nM [1].

MK-3207

A3615-5 5 mg
EUR 340
Description: MK-3207 is a new, highly selective CGRP receptor antagonist that is approximately 40- to 65-fold more potent than telcagepant for the human CGRP receptor. The IC50 is 0.12 nM and The Ki value is 0.024 nM. It is highly selective versus human AM1, AM2, CTR, and AMY3.

MK-4827

A3617-5 5 mg
EUR 209
Description: MK-4827 is a novel, selective and orally bioavailable PARP1/PARP2 inhibitor with IC50 of 3.8 nM and 2.1 nM, respevctively.MK-4827 has shown great activity against cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1 [1].

MK-5172

A3618-5 5 mg
EUR 154
Description: MK-5172 is a selective inhibitor of Hepatitis C Virus NS3/4a Protease [1].Hepatitis C (HCV) virus is a member of the Flaviviridae family of viruses in the Hepacivirus genus and encoded by a 9.6-kb positive strand RNA genome [2].

MK-6892

A3623-5 5 mg
EUR 502
Description: Description:IC50 Value: 4.0 nM (Ki for Human GPR109A) [1]MK-6892 is a highly potential GPR109A agonists.in vitro: . Despite the increased serum shift of these compounds, the representative 1e was highly potent

MK-8033

A3624-5 5 mg
EUR 466
Description: MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing.

MK-0752

A4006-5 5 mg
EUR 247
Description: MK-0752 is a potent gamma secretase inhibitor in clinical development (IC50 ~50 nM).

MK-2048

A4072-5 5 mg
EUR 270
Description: MK-2048 is a second generation inhibitor of HIV-1 integrase with IC50 values of 0.075 ?M and 0.08 ?M for subtype B and subtype C integrase, respectively.Integration of viral cDNA into the host genome is one of the definitive features of retrovirus replication.

MK-8245

A4345-5 5 mg
EUR 268
Description: MK-8245 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase (SCD) with IC50 value of 1nM [1].SCD1 represents a therapeutic target for the treatment of type II diabetes, dyslipidemia, obesity, and metabolic diseases.

MK-0941

B1207-5
EUR 185

MK-1439

B1250-5
EUR 218

MK-4101

B1255-5
EUR 218

MK-8931

B1315-5
EUR 512

MK-5108

B1344-5
EUR 262

MK-1064

B1641-5
EUR 278

MK-8745

B1942-5
EUR 153

MK-0752

B1980-5
EUR 457

MK-5172

B2118-5
EUR 185

MK-7655

B2289-5
EUR 196

MK-0557

B2317-5
EUR 196

MK-3903

B2431-5
EUR 414

MK-886

B2517-5
EUR 175

MK-5 with vented cover (polycarbonate